CUDA


Catalog No. Size PriceQuantity
M19286-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

CUDA is a potent inhibitor of soluble epoxide hydrolase (sEH), with IC50s of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively. CUDA selectively increases peroxisome proliferator-activated receptor (PPAR) alpha activity. CUDA may be valuable for the research of cardiovascular disease.

Product information

CAS Number: 479413-68-8

Molecular Weight: 340.50

Formula: C19H36N2O3

Chemical Name: 12-[(cyclohexylcarbamoyl)amino]dodecanoic acid

Smiles: OC(=O)CCCCCCCCCCCNC(=O)NC1CCCCC1

InChiKey: HPTJABJPZMULFH-UHFFFAOYSA-N

InChi: InChI=1S/C19H36N2O3/c22-18(23)15-11-6-4-2-1-3-5-7-12-16-20-19(24)21-17-13-9-8-10-14-17/h17H,1-16H2,(H,22,23)(H2,20,21,24)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 25 mg/mL (73.42 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

CUDA (10 μM; 18 hours) produces 6- and 3-fold increases of PPARalpha in COS-7 cells. CUDA does not alter PPARalpha protein expression, and it competitively inhibits the binding of Wy-14643 (pirinixic acid) to the ligand binding domain of PPARalpha, suggesting that it functions as a PPARalpha ligand.

Products are for research use only. Not for human use.

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