Autotaxin-IN-3


Catalog No. Size PriceQuantity
M19438-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Autotaxin-IN-3 is a Autotaxin(ATX) inhibitor with an IC50 of 2.4 nM, compound 33, sourced from patent WO2018212534A1.

Product information

CAS Number: 2156655-68-2

Molecular Weight: 443.46

Formula: C22H21N9O2

Chemical Name: 2-(5-{2-[(2,3-dihydro-1H-inden-2-yl)amino]pyrimidin-5-yl}-1,3,4-oxadiazol-2-yl)-1-{3H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridin-5-yl}ethan-1-one

Smiles: O=C(CC1=NN=C(O1)C1=CN=C(NC2CC3C=CC=CC=3C2)N=C1)N1CC2NN=NC=2CC1

InChiKey: YJLUBHOZZTYQIP-UHFFFAOYSA-N

InChi: InChI=1S/C22H21N9O2/c32-20(31-6-5-17-18(12-31)27-30-26-17)9-19-28-29-21(33-19)15-10-23-22(24-11-15)25-16-7-13-3-1-2-4-14(13)8-16/h1-4,10-11,16H,5-9,12H2,(H,23,24,25)(H,26,27,30)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 250 mg/mL (563.75 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Autotaxin is an enzyme which is responsible for the increase in lysophosphatidic acid in ascites and plasma, and it is a secretory enzyme important for converting lysophosphatidylchloine (LPC) into lysophosphatidic acid (LPA) as a bioactive signaling molecule.

Products are for research use only. Not for human use.

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