Description
AZD 4407 is a potent 5-lipoxygenase inhibitor.
Product information
CAS Number: 166882-70-8
Molecular Weight: 375.50
Formula: C19H21NO3S2
Chemical Name: 5-({4-[(2S,4R)-4-hydroxy-2-methyloxan-4-yl]thiophen-2-yl}sulfanyl)-1-methyl-2,3-dihydro-1H-indol-2-one
Smiles: C[C@H]1C[C@](O)(CCO1)C1C=C(SC2=CC3CC(=O)N(C)C=3C=C2)SC=1
InChiKey: MQLADKMVHOOVET-HXPMCKFVSA-N
InChi: InChI=1S/C19H21NO3S2/c1-12-10-19(22,5-6-23-12)14-9-18(24-11-14)25-15-3-4-16-13(7-15)8-17(21)20(16)2/h3-4,7,9,11-12,22H,5-6,8,10H2,1-2H3/t12-,19+/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
In view of the powerful spasmogenic actions of leukotrienes in vascular and bronchial tissue, drugs which block their biosynthesis by inhibiting 5-lipoxygenase may have therapeutic potential in a variety of inflammatory conditions including inflammatory arthropothies, asthma, psoriasis, and inflammatory bowel disease. One such compound is AZD 4407 (ZD4407).
Products are for research use only. Not for human use.
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