Description
4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.
Product information
CAS Number: 51568-18-4
Molecular Weight: 158.15
Formula: C7H10O4
Chemical Name: 4,6-dioxoheptanoic acid
Smiles: CC(=O)CC(=O)CCC(O)=O
InChiKey: WYEPBHZLDUPIOD-UHFFFAOYSA-N
InChi: InChI=1S/C7H10O4/c1-5(8)4-6(9)2-3-7(10)11/h2-4H2,1H3,(H,10,11)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (632.31 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
4,6-Dioxoheptanoic acid (Succinylacetone, SA) is examined with regard to its ability to a) inhibit the second enzyme of the heme pathway, δ-aminolevulinic acid (ALA) dehydratase, b) lower the heme concentration, and c) inhibit cell growth of murine erythroleukemia (MEL) cells in culture.
Products are for research use only. Not for human use.
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