MK-3328


Catalog No. Size PriceQuantity
M20299-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

MK-3328 is a β-Amyloid PET ligand, which exhibits high binding potency with an IC50 of 10.5 nM.

Product information

CAS Number: 1201323-97-8

Molecular Weight: 268.25

Formula: C14H9FN4O

Chemical Name: 5-{5-fluoro-[1,3]oxazolo[5,4-b]pyridin-2-yl}-1-methyl-1H-pyrrolo[2,3-b]pyridine

Smiles: CN1C=CC2=CC(=CN=C12)C1=NC2=CC=C(F)N=C2O1

InChiKey: WYQHKOHCTMNFAU-UHFFFAOYSA-N

InChi: InChI=1S/C14H9FN4O/c1-19-5-4-8-6-9(7-16-12(8)19)13-17-10-2-3-11(15)18-14(10)20-13/h2-7H,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

MK-3328 exhibits amyloid binding potency balanced with low levels of nonspecific binding.

In Vivo:

In vivo, [18F]MK-3328 demonstrates favorable kinetics, exhibiting high brain uptake and good washout in normal rhesus monkey positron emission tomography (PET) imaging studies.

Products are for research use only. Not for human use.

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