Cefotaxime sodium salt


Catalog No. Size PriceQuantity
M20313-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Cefotaxime sodium salt, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria.

Product information

CAS Number: 64485-93-4

Molecular Weight: 477.45

Formula: C16H16N5NaO7S2

Chemical Name: sodium (6R,7R)-3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Smiles: [Na+].CC(=O)OCC1CS[C@@H]2[C@H](NC(=O)/C(=N\OC)/C3=CSC(N)=N3)C(=O)N2C=1C([O-])=O

InChiKey: AZZMGZXNTDTSME-JUZDKLSSSA-M

InChi: InChI=1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 45 mg/mL (94.25 mM; Need ultrasonic). H2O : 50 mg/mL (104.72 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Cefotaxime exhibits an MIC of 0.0625 mg/L for V. vulnificus CMCP6.

In Vivo:

The combination of ciprofloxacin and cefotaxime is more effective in clearing V. vulnificus in vivo than previously used regimens.

Products are for research use only. Not for human use.

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