TRAF-STOP inhibitor 6877002


Catalog No. Size PriceQuantity
M20583-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

TRAF-STOP inhibitor 6877002, is a selective inhibitor of CD40-TRAF6 interaction, compound VII, shows inhibition of NF-κB activation in RAW cells, extracted from patent WO2014033122A1. TRAF-STOP 6877002 prevents the progression of established atherosclerosis in mice, reduces leukocyte recruitment and reduces macrophage activation; reduces macrophage proliferation in atherosclerotic plaques.

Product information

CAS Number: 433249-94-6

Molecular Weight: 251.32

Formula: C17H17NO

Chemical Name: (2E)-3-[(2,5-dimethylphenyl)amino]-1-phenylprop-2-en-1-one

Smiles: CC1C=CC(C)=CC=1N/C=C/C(=O)C1C=CC=CC=1

InChiKey: SARYOFMRLSHZFE-ZHACJKMWSA-N

InChi: InChI=1S/C17H17NO/c1-13-8-9-14(2)16(12-13)18-11-10-17(19)15-6-4-3-5-7-15/h3-12,18H,1-2H3/b11-10+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 125 mg/mL (497.37 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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