CCR1 antagonist 8


Catalog No. Size PriceQuantity
M20637-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

CCR1 antagonist 8 (compound 19n), a third azaindazole series compound, is a CCR1 antagonist, with an IC50 of 1.8 nM in Ca2+ flux assay.

Product information

CAS Number: 1295298-26-8

Molecular Weight: 451.47

Formula: C22H18FN5O3S

Chemical Name: 1-(4-fluorophenyl)-N-[1-(2-methanesulfonylpyridin-4-yl)cyclopropyl]-1H-pyrazolo[3,4-c]pyridine-4-carboxamide

Smiles: CS(=O)(=O)C1C=C(C=CN=1)C1(CC1)NC(=O)C1=CN=CC2=C1C=NN2C1C=CC(F)=CC=1

InChiKey: PXQATVYJKMMHAU-UHFFFAOYSA-N

InChi: InChI=1S/C22H18FN5O3S/c1-32(30,31)20-10-14(6-9-25-20)22(7-8-22)27-21(29)18-11-24-13-19-17(18)12-26-28(19)16-4-2-15(23)3-5-16/h2-6,9-13H,7-8H2,1H3,(H,27,29)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 10 mg/mL (22.15 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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