Description
Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin.
Product information
CAS Number: 102-37-4
Molecular Weight: 208.21
Formula: C11H12O4
Chemical Name: ethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
Smiles: CCOC(=O)/C=C/C1C=C(O)C(O)=CC=1
InChiKey: WDKYDMULARNCIS-GQCTYLIASA-N
InChi: InChI=1S/C11H12O4/c1-2-15-11(14)6-4-8-3-5-9(12)10(13)7-8/h3-7,12-13H,2H2,1H3/b6-4+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 250 mg/mL (1200.71 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Ethyl Caffeate markedly suppresses the lipopolysaccharide (LPS)-induced nitric oxide (NO) production with IC50 of 5.5 μg/ml.
Products are for research use only. Not for human use.
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