AN2718


Catalog No. Size PriceQuantity
M20726-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

AN2718 inhibits fungal growth by blocking protein synthesis using the oxaborole tRNA trapping (OBORT) mechanism.

Product information

CAS Number: 174672-06-1

Molecular Weight: 168.39

Formula: C7H6BClO2

Chemical Name: 5-chloro-1,3-dihydro-2,1-benzoxaborol-1-ol

Smiles: OB1OCC2=CC(Cl)=CC=C21

InChiKey: HMAFTPZYFJFEHK-UHFFFAOYSA-N

InChi: InChI=1S/C7H6BClO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 250 mg/mL (1484.65 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

AN2718 inhibits cytoplasmic LeuRS from molds, A. fumigatus, and from yeasts, C. albicans, with an IC50 of 2 μM and 4.2 μM, respectively. AN2718 has good MIC90 activity against the dermatophytes, T. rubrum and T.mentagrophytes.

Products are for research use only. Not for human use.

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