JNJ 303


Catalog No. Size PriceQuantity
M20760-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

JNJ 303 is a potent IKs blocker with an IC50 value of 64 nM. JNJ 303 does not have any effects on other cardiac channels at concentrations of 3.3 μM for INa, Ica, Ito, and IKr. JNJ 303 induces QT-prolongations and causes unprovoked torsades de pointes (TdP).

Product information

CAS Number: 878489-28-2

Molecular Weight: 440.98

Formula: C21H29ClN2O4S

Chemical Name: 2-(4-chlorophenoxy)-2-methyl-N-[(1R,2s,3S,5s,7s)-5-methanesulfonamidoadamantan-2-yl]propanamide

Smiles: CC(C)(OC1C=CC(Cl)=CC=1)C(=O)N[C@@H]1[C@@H]2C[C@H]3C[C@](C[C@@H]1C3)(C2)NS(C)(=O)=O

InChiKey: OSGIRCJRKSAODN-HPMFMUNCSA-N

InChi: InChI=1S/C21H29ClN2O4S/c1-20(2,28-17-6-4-16(22)5-7-17)19(25)23-18-14-8-13-9-15(18)12-21(10-13,11-14)24-29(3,26)27/h4-7,13-15,18,24H,8-12H2,1-3H3,(H,23,25)/t13-,14-,15+,18-,21-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 62.5 mg/mL (141.73 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

You may also like

Recently viewed