Description
PG106 is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC50=210 nM) and has noactivity at hMC4 receptors (EC50=9900 nM) and hMC5 receptor.
Product information
CAS Number: 944111-22-2
Molecular Weight: 1008.18
Formula: C51H69N13O9
Chemical Name: (3S,6S,9R,16S,24S)-6-(3-carbamimidamidopropyl)-2,5,8,11,15,18-hexahydroxy-16-[(Z)-{1-hydroxy-2-[(Z)-(1-hydroxyethylidene)amino]hexylidene}amino]-3-[(1H-indol-3-yl)methyl]-9-[(naphthalen-2-yl)methyl]-1,4,7,10,14,19-hexaazacyclotetracosa-1,4,7,10,14,18-hexaene-24-carboximidic acid
Smiles: C/C(/O)=N/C(CCCC)/C(/O)=N/[C@H]1CC(O)=NCCCC[C@H](N=C(O)[C@H](CC2=CNC3=CC=CC=C23)N=C(O)[C@H](CCCNC(N)=N)N=C(O)[C@@H](CC2=CC3=CC=CC=C3C=C2)N=C(O)CCN=C1O)C(=N)O |c:22,38,49,66,t:15,71|
InChiKey: ZFZDDBJAFMOQSH-JHMPFZGISA-N
InChi: InChI=1S/C51H69N13O9/c1-3-4-15-38(59-30(2)65)47(70)64-42-28-44(67)55-22-10-9-17-37(45(52)68)61-50(73)41(27-34-29-58-36-16-8-7-14-35(34)36)63-48(71)39(18-11-23-57-51(53)54)62-49(72)40(60-43(66)21-24-56-46(42)69)26-31-19-20-32-12-5-6-13-33(32)25-31/h5-8,12-14,16,19-20,25,29,37-42,58H,3-4,9-11,15,17-18,21-24,26-28H2,1-2H3,(H2,52,68)(H,55,67)(H,56,69)(H,59,65)(H,60,66)(H,61,73)(H,62,72)(H,63,71)(H,64,70)(H4,53,54,57)/t37-,38?,39-,40+,41-,42-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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