Description
BW-A 78U is a PDE4 inhibitor with an IC50 of 3 μM.
Product information
CAS Number: 101155-02-6
Molecular Weight: 257.27
Formula: C13H12FN5
Chemical Name: 9-[(2-fluorophenyl)methyl]-N-methyl-9H-purin-6-amine
Smiles: CNC1=NC=NC2=C1N=CN2CC1=CC=CC=C1F
InChiKey: MZABAGHILOTTOD-UHFFFAOYSA-N
InChi: InChI=1S/C13H12FN5/c1-15-12-11-13(17-7-16-12)19(8-18-11)6-9-4-2-3-5-10(9)14/h2-5,7-8H,6H2,1H3,(H,15,16,17)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 150 mg/mL (583.05 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
BW-A 78U is a PDE4 inhibitor with an IC50 of 3 μM. BW-A 78U fails to significantly inhibit arachidonate release. BW-A 78U is ineffective to inhibit the lipopolysaccharide (LPS)-induced TNF-α release.
Products are for research use only. Not for human use.
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