Description
IL-17A antagonist 1 (compound 1) is an IL-17A antagonist, with a Kd of 0.66 μM and an IC50 of 1.14 μM.
Product information
CAS Number: 2205034-18-8
Molecular Weight: 604.71
Formula: C33H41FN6O4
Chemical Name: (2S)-N-{4-[2-(2-{1-[(dimethylcarbamoyl)methyl]cyclopentyl}acetamido)ethyl]phenyl}-3-(2-fluorophenyl)-2-[(1-methyl-1H-pyrazol-5-yl)formamido]propanamide
Smiles: CN(C)C(=O)CC1(CC(=O)NCCC2C=CC(=CC=2)NC(=O)[C@H](CC2=CC=CC=C2F)NC(=O)C2=CC=NN2C)CCCC1
InChiKey: VWRXSIAIHJZTCV-MHZLTWQESA-N
InChi: InChI=1S/C33H41FN6O4/c1-39(2)30(42)22-33(16-6-7-17-33)21-29(41)35-18-14-23-10-12-25(13-11-23)37-31(43)27(20-24-8-4-5-9-26(24)34)38-32(44)28-15-19-36-40(28)3/h4-5,8-13,15,19,27H,6-7,14,16-18,20-22H2,1-3H3,(H,35,41)(H,37,43)(H,38,44)/t27-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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