6-Biopterin


Catalog No. Size PriceQuantity
M21014-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

6-Biopterin (L-Biopterin), a pterin derivative, is a NO synthase cofactor.

Product information

CAS Number: 22150-76-1

Molecular Weight: 237.22

Formula: C9H11N5O3

Chemical Name: 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-4,8-dihydropteridin-4-one

Smiles: C[C@H](O)[C@H](O)C1=CNC2=NC(N)=NC(=O)C2=N1

InChiKey: LHQIJBMDNUYRAM-DZSWIPIPSA-N

InChi: InChI=1S/C9H11N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h2-3,6,15-16H,1H3,(H3,10,11,13,14,17)/t3-,6-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 12.5 mg/mL (52.69 mM; ultrasonic and warming and heat to 75°C).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

6-biopterin is extremely cytotoxic to human melanocytes under in vitro conditions. Thioredoxin reductase has the capacity to reduce 6-biopterin to q-BH2 where further reduction to 6-BH4 follows via dihydropteridine reductase or reduced glutathione. (6R)5,6,7,8 tetrahydrobiopterin undergoes redox-cycling by its oxidation to quinonoid dihydrobiopterin and to 6-biopterin through consecutive two electron oxidation reactions.

Products are for research use only. Not for human use.

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