Description
GNE-0946 is a potent and selective RORγ( RORc) agonist with an EC50 value of 4 nM for HEK-293 cell.
Product information
CAS Number: 1677667-24-1
Molecular Weight: 460.79
Formula: C22H12ClF3N2O4
Chemical Name: 4-{3-[2-chloro-6-(trifluoromethyl)benzoyl]imidazo[1,5-a]pyridin-1-yl}-2-hydroxybenzoic acid
Smiles: OC(=O)C1=CC=C(C=C1O)C1N=C(C(=O)C2C(Cl)=CC=CC=2C(F)(F)F)N2C=CC=CC2=1
InChiKey: UAAUZNSONHHQQI-UHFFFAOYSA-N
InChi: InChI=1S/C22H12ClF3N2O4/c23-14-5-3-4-13(22(24,25)26)17(14)19(30)20-27-18(15-6-1-2-9-28(15)20)11-7-8-12(21(31)32)16(29)10-11/h1-10,29H,(H,31,32)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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