AF40431


Catalog No. Size PriceQuantity
M21232-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

AF40431, the first reported small-molecule ligand of sortilin, has an IC50 of 4.4 µM and a Kd of 0.7 µM . AF40431 is bound in the neurotensin-binding site of sortilin.

Product information

CAS Number: 181125-92-8

Molecular Weight: 319.35

Formula: C17H21NO5

Chemical Name: (2S)-2-{[(7-hydroxy-4-methyl-2-oxo-2H-chromen-8-yl)methyl]amino}-4-methylpentanoic acid

Smiles: CC1=CC(=O)OC2C1=CC=C(O)C=2CN[C@@H](CC(C)C)C(O)=O

InChiKey: YPJLUCAXHFPZJD-ZDUSSCGKSA-N

InChi: InChI=1S/C17H21NO5/c1-9(2)6-13(17(21)22)18-8-12-14(19)5-4-11-10(3)7-15(20)23-16(11)12/h4-5,7,9,13,18-19H,6,8H2,1-3H3,(H,21,22)/t13-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 25 mg/mL (78.28 mM; ultrasonic and adjust pH to 1 with TFA).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

You may also like

Recently viewed