Ibotenic acid


Catalog No. Size PriceQuantity
M21289-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites.

Product information

CAS Number: 2552-55-8

Molecular Weight: 158.11

Formula: C5H6N2O4

Chemical Name: (2S)-2-amino-2-(3-oxo-2,3-dihydro-1,2-oxazol-5-yl)acetic acid

Smiles: N[C@H](C(O)=O)C1=CC(=O)NO1

InChiKey: IRJCBFDCFXCWGO-BYPYZUCNSA-N

InChi: InChI=1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)/t4-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 5 mg/mL (31.62 mM; Need ultrasonic). H2O : 5 mg/mL (31.62 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Ibotenic acid (Ibo) is capable of acting at both NMDA and trans-ACPD receptors in the CNS, although only activation of NMDA receptors is involved in Ibo neurotoxicity. Ibotenic acid is toxic to cortical neurons exposes for 5 min with an EC50=77.3±8 μM (n=5) as measured by release of lactate dehydrogenase to the culture media.

Products are for research use only. Not for human use.

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