Description
GSK9027, as a non-steroidal glucocorticoid receptor (GR) agonist, behaves as a partial agonist on the 2×glucocorticoid response element (GRE) reporter system, and achieves intrinsic activities relative to dexamethasone.
Product information
CAS Number: 1229096-88-1
Molecular Weight: 525.52
Formula: C27H19F4N3O2S
Chemical Name: N-{4-[1-(4-fluorophenyl)-1H-indazol-5-yl]-3-(trifluoromethyl)phenyl}-1-phenylmethanesulfonamide
Smiles: O=S(=O)(CC1C=CC=CC=1)NC1=CC(=C(C=C1)C1C=C2C=NN(C3=CC=C(F)C=C3)C2=CC=1)C(F)(F)F
InChiKey: DXBJGDVBQPEMOB-UHFFFAOYSA-N
InChi: InChI=1S/C27H19F4N3O2S/c28-21-7-10-23(11-8-21)34-26-13-6-19(14-20(26)16-32-34)24-12-9-22(15-25(24)27(29,30)31)33-37(35,36)17-18-4-2-1-3-5-18/h1-16,33H,17H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
GSK9027 demonstrates reduced 2×GRE reporter activation and is partial agonists.
Products are for research use only. Not for human use.
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