Description
Cl-HIBO is a highly subtype-selective GluR1/2 agonist (EC50=4.7 and 1.7 μM, respectively). Cl-HIBO is a potent AMPA receptor agonist (IC50=0.22 μM). Cl-HIBO has desensitizing properties.
Product information
CAS Number: 909400-43-7
Molecular Weight: 206.58
Formula: C6H7ClN2O4
Chemical Name: (2S)-2-amino-3-(4-chloro-3-oxo-2,3-dihydro-1,2-oxazol-5-yl)propanoic acid
Smiles: N[C@@H](CC1ONC(=O)C=1Cl)C(O)=O
InChiKey: FDSXCQTXUSQQFH-REOHCLBHSA-N
InChi: InChI=1S/C6H7ClN2O4/c7-4-3(13-9-5(4)10)1-2(8)6(11)12/h2H,1,8H2,(H,9,10)(H,11,12)/t2-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Cl-HIBO is a strongly desensitizing full agonist at GluR1.
Products are for research use only. Not for human use.
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