SPHINX31


Catalog No. Size PriceQuantity
M21584-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

SPHINX31 is a potent and selective inhibitor of serine/arginine-rich protein kinase 1 (SRPK1), with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 is a potential topical therapeutic for neovascular eye disease.

Product information

CAS Number: 1818389-84-2

Molecular Weight: 507.51

Formula: C27H24F3N5O2

Chemical Name: N-(2-{4-[(pyridin-2-yl)methyl]piperazin-1-yl}-5-(trifluoromethyl)phenyl)-5-(pyridin-4-yl)furan-2-carboxamide

Smiles: O=C(NC1=CC(=CC=C1N1CCN(CC2=CC=CC=N2)CC1)C(F)(F)F)C1=CC=C(O1)C1C=CN=CC=1

InChiKey: VURLRACCOCGFDB-UHFFFAOYSA-N

InChi: InChI=1S/C27H24F3N5O2/c28-27(29,30)20-4-5-23(35-15-13-34(14-16-35)18-21-3-1-2-10-32-21)22(17-20)33-26(36)25-7-6-24(37-25)19-8-11-31-12-9-19/h1-12,17H,13-16,18H2,(H,33,36)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 17.33 mg/mL (34.15 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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