PF-03654746 Tosylate


Catalog No. Size PriceQuantity
M21602-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

PF-03654746 Tosylate is a potent and selective histamine H3 receptor antagonist with high brain penetration. PF-03654746 Tosylate reduces allergen-induced nasal symptoms. PF-03654746 Tosylate has potential for treatment of human cognitive disorders, improves cognitive efficacy and disease-modifying effects in Alzheimer's disease (AD).

Product information

CAS Number: 1039399-17-1

Molecular Weight: 494.59

Formula: C25H32F2N2O4S

Chemical Name: (1s,3s)-N-ethyl-3-fluoro-3-{3-fluoro-4-[(pyrrolidin-1-yl)methyl]phenyl}cyclobutane-1-carboxamide; 4-methylbenzene-1-sulfonic acid

Smiles: CC1C=CC(=CC=1)S(O)(=O)=O.CCNC(=O)[C@@H]1C[C@](F)(C1)C1C=C(F)C(CN2CCCC2)=CC=1

InChiKey: IKAYTZLLIWAEDV-PHNBSMHASA-N

InChi: InChI=1S/C18H24F2N2O.C7H8O3S/c1-2-21-17(23)14-10-18(20,11-14)15-6-5-13(16(19)9-15)12-22-7-3-4-8-22;1-6-2-4-7(5-3-6)11(8,9)10/h5-6,9,14H,2-4,7-8,10-12H2,1H3,(H,21,23);2-5H,1H3,(H,8,9,10)/t14-,18+;

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: H2O : ≥ 8.4 mg/mL (16.98 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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