Catalog No. Size PriceQuantity
M21671-C Contact sales@xcessbio.com for quotation $100Unavailable


exo-IWR-1, an inactive stereoisomer of Endo-IWR-1, is a negative control of IWR-1 (HY-12238). IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway.

Product information

CAS Number: 1127442-87-8

Molecular Weight: 409.44

Formula: C25H19N3O3

Chemical Name: 4-[(1R,2R,6S,7S)-3,5-dioxo-4-azatricyclo[²,⁶]dec-8-en-4-yl]-N-(quinolin-8-yl)benzamide

Smiles: O=C(NC1=CC=CC2=CC=CN=C21)C1C=CC(=CC=1)N1C(=O)[C@@H]2[C@@H]3C[C@@H](C=C3)[C@@H]2C1=O


InChi: InChI=1S/C25H19N3O3/c29-23(27-19-5-1-3-14-4-2-12-26-22(14)19)15-8-10-18(11-9-15)28-24(30)20-16-6-7-17(13-16)21(20)25(28)31/h1-12,16-17,20-21H,13H2,(H,27,29)/t16-,17+,20+,21-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

exo-IWR-1 (10 μM) does not influence the number of 293T cells infected with bunyaviruses. Exo-IWR-1 had no effect on RVFV MP12-GFP infection when cells were either pretreated or treated 1 hpi.

Products are for research use only. Not for human use.

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