A 1070722


Catalog No. Size PriceQuantity
M21678-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

A 1070722 is a potent and selective glycogen synthase kinase 3 (GSK-3) inhibitor, with a Ki of 0.6 nM for both GSK-3α and GSK-3β. A 1070722 can penetrate the blood-brain barrier (BBB) and accumulates in brain regions, thus potential for PET radiotracer for the quantification of GSK-3 in brain.

Product information

CAS Number: 1384424-80-9

Molecular Weight: 362.31

Formula: C17H13F3N4O2

Chemical Name: (Z)-N'-(7-methoxyquinolin-4-yl)-N-[6-(trifluoromethyl)pyridin-2-yl]carbamimidic acid

Smiles: COC1=CC2=NC=CC(/N=C(\O)/NC3=CC=CC(=N3)C(F)(F)F)=C2C=C1

InChiKey: VQPBIJGXSXEOCU-UHFFFAOYSA-N

InChi: InChI=1S/C17H13F3N4O2/c1-26-10-5-6-11-12(7-8-21-13(11)9-10)22-16(25)24-15-4-2-3-14(23-15)17(18,19)20/h2-9H,1H3,(H2,21,22,23,24,25)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 83.33 mg/mL (230.00 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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