SR121566A


Catalog No. Size PriceQuantity
M21761-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

SR121566A is a novel non-peptide Glycoprotein IIb/IIIa (GP IIb-IIIa) antagonist, which can inhibit ADP-, arachidonic acid- and collagen-induced human platelet aggregation with IC50s of 46±7.5, 56±6 and 42±3 nM, respectively.

Product information

CAS Number: 180144-61-0

Molecular Weight: 431.51

Formula: C20H25N5O4S

Chemical Name: 3-{[4-(4-carbamimidoylphenyl)-1,3-thiazol-2-yl][1-(carboxymethyl)piperidin-4-yl]amino}propanoic acid

Smiles: NC(=N)C1C=CC(=CC=1)C1=CSC(=N1)N(CCC(O)=O)C1CCN(CC(O)=O)CC1

InChiKey: LYIQNVKSTSEEEG-UHFFFAOYSA-N

InChi: InChI=1S/C20H25N5O4S/c21-19(22)14-3-1-13(2-4-14)16-12-30-20(23-16)25(10-7-17(26)27)15-5-8-24(9-6-15)11-18(28)29/h1-4,12,15H,5-11H2,(H3,21,22)(H,26,27)(H,28,29)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

SR121566A leads to dose-dependent increases in TTO, a statistically significant increase being observed at the doses of 0.3 mg/kg (473%) and 30 mg/kg (771%), respectively.

Products are for research use only. Not for human use.

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