Oxantel pamoate

Catalog No. Size PriceQuantity
M21922-C Contact sales@xcessbio.com for quotation $100Unavailable


Oxantel pamoate is a widely available dewormer, potently against Trichuris muris and Hookworms.

Product information

CAS Number: 68813-55-8

Molecular Weight: 604.65

Formula: C36H32N2O7

Chemical Name: 3-[(E)-2-(1-methyl-1,4,5,6-tetrahydropyrimidin-2-yl)ethenyl]phenol; 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid

Smiles: CN1CCCN=C1/C=C/C1=CC(O)=CC=C1.OC(=O)C1C=C2C=CC=CC2=C(CC2=C3C=CC=CC3=CC(=C2O)C(O)=O)C=1O


InChi: InChI=1S/C23H16O6.C13H16N2O/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-15-9-3-8-14-13(15)7-6-11-4-2-5-12(16)10-11/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-7,10,16H,3,8-9H2,1H3/b;7-6+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 50 mg/mL (82.69 mM). H2O : 0.67 mg/mL (1.11 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

The activity of the veterinary drug Oxantel pamoate is studied against Trichuris muris, Ancylostoma ceylanicum and Necator americanus. An ED50s of 4.7 mg/kg is calculated for Oxantel pamoate against T. muris in mice. Combinations of Oxantel pamoate with pyrantel pamoate behaved antagonistically (combination index (CI)=2.53). Oxantel pamoate combined with Levamisole, Albendazole or Ivermectin using ratios based on their ED50s reveals antagonistic effects (CI=1.27, 1.90 and 1.27, respectively). A highly synergistic effect (CI=0.15) is observed when Oxantel pamoate-mebendazole is administered to T. muris-infected mice. Oxantel pamoate (10 mg/kg) lacks activity against Ancylostoma ceylanicum and Necator americanus.

Products are for research use only. Not for human use.

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