BMY-25271


Catalog No. Size PriceQuantity
M21932-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

BMY-25271 is a histamine H2 receptor antagonist.

Product information

CAS Number: 78441-82-4

Molecular Weight: 329.44

Formula: C12H19N5O2S2

Chemical Name: 3-amino-4-({2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)sulfanyl]ethyl}amino)-1λ⁴,2,5-thiadiazol-1-one

Smiles: CN(C)CC1=CC=C(CSCCNC2=NS(=O)N=C2N)O1

InChiKey: IZTBLLPMEZOKSV-UHFFFAOYSA-N

InChi: InChI=1S/C12H19N5O2S2/c1-17(2)7-9-3-4-10(19-9)8-20-6-5-14-12-11(13)15-21(18)16-12/h3-4H,5-8H2,1-2H3,(H2,13,15)(H,14,16)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

BMY-25271 is a histamine H2 receptor antagonist. The dose response curves are parallel and oral ED50 values derived from probit analysis are 0.093, 0.97 and 6.9 mg/kg for BMY-25271, ranitidine and cimetidine, respectively. BMY-25271, therefore, is about 10 and 74 times more potent than ranitidine and cimetidine, respectively. Pretreatment with the highest dose of BMY-25271 does not significantly affect the absorption of aspirin or the formation of its major metabolite, salicylic acid.

Products are for research use only. Not for human use.

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