Description
Kainic acid is a potent agonist at excitatory amino acid receptor subtypes in the CNS.
Product information
CAS Number: 487-79-6
Molecular Weight: 213.23
Formula: C10H15NO4
Chemical Name: (2S,3S,4S)-3-(carboxymethyl)-4-(prop-1-en-2-yl)pyrrolidine-2-carboxylic acid
Smiles: CC(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O
InChiKey: VLSMHEGGTFMBBZ-OOZYFLPDSA-N
InChi: InChI=1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: H2O : 25 mg/mL (117.24 mM; ultrasonic and warming and heat to 60°C).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
Kainic acid is a potent agonist at excitatory amino acid receptor subtypes in the CNS. HO-I levels are significantly enhanced one, three and seven days after i.c.v, injection of Kainic acid. One day after i.c.v, injection of Kainic acid, the HO-I protein level reaches a maximum and then decreases, but is still significantly enhanced versus the vehicle-injected group. After i.c.v. injection of Kainic acid, HO-I-immunoreactivity is strongly induced not only in the CA3 but also widely in the whole hippocampus.
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