Fusapyrone


Catalog No. Size PriceQuantity
M22043-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Fusapyrone, a broad-spectrum antifungal metabolite, is isolated from several Fusarium species. Structurally, fusapyrone consists of a 4-deoxy-β-xylo-hexopyranosyl C-glycosyl moiety bound to the C-6 of the 2-pyrone ring and a highly functionalized aliphatic chain. Fusapyrone exhibited low zoo-toxicity, as evidenced by a lack of toxicity against Artemia salina. Fusapyrone exerted considerable antifungal activity against several plant mycotoxigenic, pathogenic, and human pathogenic filamentous fungi, including Aspergillus flavus, Aspergillus niger, Aspergillus parasiticus, and Aspergillus fumigatus . Additionally, it had been investigated as a useful candidate for the control of postharvest crop diseases, including blocking the growth of ochratoxin-producing strains of Aspergillus section Nigri in wine grapes. However, fusapyrone was found to be ineffective toward yeasts isolated from fruits and plants and not toxic to Artemia salina (brine shrimp). The mechanism of action of fusapyrone is unknown and the structure of fusapyrone was revised in 2006. In vitro: Up to now, in vitro study of fusapyrone is still in the development stage. In vivo: Up to now, in vivo study of fusapyrone is still in the development stage.

Product information

CAS Number: 156856-31-4

Molecular Weight: 606.79

Formula: C34H54O9

Chemical Name: 3-[(2S,3R,4S,6S)-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]-6-[(4E,6E)-8-[(1Z)-2,4-dimethyldec-1-en-1-yl]-3,9-dihydroxy-2,6-dimethylnona-4,6-dien-2-yl]-2-hydroxy-4H-pyran-4-one

Smiles: CC(C/C(/C)=C\C(CO)/C=C(\C)/C=C/C(O)C(C)(C)C1=CC(=O)C([C@@H]2O[C@@H](C[C@H](O)[C@H]2O)CO)=C(O)O1)CCCCCC

InChiKey: VMIZPSIJERGBNI-ZBNIOBMFSA-N

InChi: InChI=1S/C34H54O9/c1-7-8-9-10-11-21(2)14-23(4)16-24(19-35)15-22(3)12-13-28(39)34(5,6)29-18-26(37)30(33(41)43-29)32-31(40)27(38)17-25(20-36)42-32/h12-13,15-16,18,21,24-25,27-28,31-32,35-36,38-41H,7-11,14,17,19-20H2,1-6H3/b13-12+,22-15+,23-16-/t21?,24?,25-,27-,28?,31+,32-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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