Vibunazole (BAY-N-7133)

Catalog No. Size PriceQuantity
M22073-C Contact for quotation $100Unavailable


Vibunazole is a new antifungal azole. Vibunazole is an antifungal azole. Low concentrations of all three drugs inhibit Coccidioides immitis, strain Silveira, in vitro with a descending order of activity ketoconazole>Vibunazole>BAY 1 9139. The untreated, infected mice lost weight initially and progressively, whereas treated mice gain weight after an initial loss with Vibunazole (all doses), BAY 1 9139 and ketoconazole at 2.5 mg/kg/day. With both Vibunazole and BAY 1 9139, the 5 and 10 mg/kg doses yield serum concentrations exceeding the MICs for the Coccidioides immitis test strain (0.8 and 1.5 μg/mL respectively) for periods in excess of 30 min after injection. . Hoeprich PD, et al. Activity of BAY n 7133 and BAY 1 9139 in vitro and in experimental murine coccidioidomycosis. Eur J Clin Microbiol. 1985 Aug;4(4):400-3.

Product information

CAS Number: 80456-55-9

Molecular Weight: 309.79

Formula: C15H20ClN3O2

Chemical Name: 1-(4-chlorophenoxy)-3,3-dimethyl-2-[(1H-1,2,4-triazol-1-yl)methyl]butan-2-ol

Smiles: CC(C)(C)C(O)(COC1C=CC(Cl)=CC=1)CN1C=NC=N1


InChi: InChI=1S/C15H20ClN3O2/c1-14(2,3)15(20,8-19-11-17-10-18-19)9-21-13-6-4-12(16)5-7-13/h4-7,10-11,20H,8-9H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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