Cannabidiol dimethyl ether


Catalog No. Size PriceQuantity
M22342-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Cannabidiol dimethyl ether (CBDD) is a cannabidiol derivative that potently and selectively inhibits 15-LOX with an IC50 value of 0.28 μM. 15-LOX can oxygenate cholesterol esters in the low-density lipoprotein (LDL) particle. Thus, 15-LOX has been involved in the development of atherosclerosis, and CBDD may be a useful prototype for producing medicines for atherosclerosis . CBDD showed a potent inhibitory effect on the catalytic activity of cytochrome P450 2C19 with an IC50 value of 14.8 μΜ . CBDD inhibited the CYP2B6 activity with the IC50values of 75.7 μM . Cytochrome P450 enzymes have been isolated from numerous mammalian tissues such as liver, kidney, lung, intestine, adrenal cortex. Cytochrome P450 enzymes have also existed in insects, plants, yeasts, and bacteria. Cytochrome P450 has been known to catalyze hydroxylations, epoxidations, N-, S-, and O-dealkylations, N-oxidations, sulfoxidations, dehalogenations, and other reactions .

Product information

CAS Number: 1242-67-7

Molecular Weight: 342.51

Formula: C23H34O2

Chemical Name: 1,3-dimethoxy-2-[(1R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]-5-pentylbenzene

Smiles: CCCCCC1C=C(OC)C([C@@H]2C=C(C)CCC2C(C)=C)=C(C=1)OC

InChiKey: UYBGHBAVRNATET-GFOWMXPYSA-N

InChi: InChI=1S/C23H34O2/c1-7-8-9-10-18-14-21(24-5)23(22(15-18)25-6)20-13-17(4)11-12-19(20)16(2)3/h13-15,19-20H,2,7-12H2,1,3-6H3/t19?,20-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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