Guvacoline (hydrobromide)


Catalog No. Size PriceQuantity
M22451-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Target: atrial and ileal muscarinic receptors IC50: 2.1 mM for growth inhibition of human buccal epithelial cells Guvacoline is a kind of natural alkaloid which is found in areca nuts that is related to the nootropic, arecoline. Guvacoline can function as a full agonist of atrial and ileal muscarinic receptors. In Vitro: In human buccal epithelial cells, Guvacoline could significantly decrease the colony-formation efficiency in a dose dependent manner, with the IC50 value of 2.1 mM. Besides, Guvacoline could also dose-dependently reduce the amount of total free low-molecular-weight thiols (0.88 mM Guvacoline caused 25% decrease) and increase the number of single strand breaks . In Vivo: No data available recently. Clinical trial: No data available recently.

Product information

CAS Number: 17210-51-4

Molecular Weight: 222.08

Formula: C7H12BrNO2

Chemical Name: methyl 1,2,5,6-tetrahydropyridine-3-carboxylate hydrobromide

Smiles: Br.COC(=O)C1CNCCC=1

InChiKey: DOXOETUWVNVADB-UHFFFAOYSA-N

InChi: InChI=1S/C7H11NO2.BrH/c1-10-7(9)6-3-2-4-8-5-6;/h3,8H,2,4-5H2,1H3;1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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