GBLD 345

Catalog No. Size PriceQuantity
M22528-C Contact for quotation $100Unavailable


GBLD 345 is a potent agonist of benzodiazepine receptor. Benzodiazepine receptor is an allosteric modulatory site on GABAA receptor . The GABAA receptor is a ligand-gated ion channel and activated by γ-aminobutyric acid (GABA). The GABAA receptor selectively permits Cl- through its pore and results in hyperpolarization of the neuron, which causes an inhibitory effect on neurotransmission. GBLD 345 is a potent benzodiazepine receptor agonist with IC50 value of 1 nM against diazepam.

Product information

CAS Number: 122479-08-7

Molecular Weight: 375.42

Formula: C21H21N5O2

Chemical Name: 4-[(6E)-3-methoxy-6-{[(3-methoxyphenyl)methyl]imino}-5H,6H-imidazo[1,2-b]pyridazin-2-yl]aniline

Smiles: COC1=CC=CC(C/N=C2\C=CC3=NC(=C(OC)N3N\2)C2=CC=C(N)C=C2)=C1


InChi: InChI=1S/C21H21N5O2/c1-27-17-5-3-4-14(12-17)13-23-18-10-11-19-24-20(21(28-2)26(19)25-18)15-6-8-16(22)9-7-15/h3-12H,13,22H2,1-2H3,(H,23,25)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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