Description
Inhibitor of dipeptidyl peptidase IV (DPP-IV) (IC50 = 104 nM) that displays selectivity over enzymes with DPP-like activity (IC50 > 30 μM). Increases plasma GLP-1 levels and improves glucose tolerance in diabetic mice following oral glucose challenge.
Product information
CAS Number: 866396-34-1
Molecular Weight: 312.80
Formula: C14H21ClN4O2
Chemical Name: (2R,5S)-1-(2-{[1-(hydroxymethyl)cyclopentyl]amino}acetyl)pyrrolidine-2,5-dicarbonitrile hydrochloride
Smiles: Cl.N#C[C@@H]1CC[C@H](C#N)N1C(=O)CNC1(CO)CCCC1
InChiKey: RHCWAHDCHQTNBR-IWKKHLOMSA-N
InChi: InChI=1S/C14H20N4O2.ClH/c15-7-11-3-4-12(8-16)18(11)13(20)9-17-14(10-19)5-1-2-6-14;/h11-12,17,19H,1-6,9-10H2;1H/t11-,12+;
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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