2-MPMDQ


Catalog No. Size PriceQuantity
M22700-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

2-MPMDQ is a potent and selective antagonist of α1-adrenoceptor . α1-adrenoceptor is a G protein-coupled receptor and mediates noradrenaline and adrenaline signal in the central and peripheral nervous systems. Also, α1-adrenoceptor mediates smooth muscle contraction. 2-MPMDQ is a potent and selective α1-adrenoceptor antagonist. In spontaneously hypertensive rats, 2-MPMDQ showed antihypertensive activity .

Product information

CAS Number: 149847-77-8

Molecular Weight: 405.49

Formula: C23H27N5O2

Chemical Name: (2R)-2-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-6-methyl-2H,3H,5H,6H-imidazo[1,2-c]quinazolin-5-one

Smiles: CN1C(=O)N2C[C@@H](CN3CCN(CC3)C3=CC=CC=C3OC)N=C2C2=CC=CC=C12

InChiKey: OULFYKAESNCMFJ-QGZVFWFLSA-N

InChi: InChI=1S/C23H27N5O2/c1-25-19-8-4-3-7-18(19)22-24-17(16-28(22)23(25)29)15-26-11-13-27(14-12-26)20-9-5-6-10-21(20)30-2/h3-10,17H,11-16H2,1-2H3/t17-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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