Arachidonoyl amide

Catalog No. Size PriceQuantity
M22705-C Contact for quotation $100Unavailable


Arachidonoyl amide is a CB1 receptor agonist . The cannabinoid receptor type 1, abbreviated as CB1, is a G protein-coupled cannabinoid receptor expressed primarily in the central and peripheral nervous system. CB1 receptor has been implicated in maintaining the homeostasis in health and disease. Overexpression of CB1 receptor has been found in human hepatocellular carcinoma tumor samples and other human prostate cancer cells . Arachidonoyl amide is an analog of anandamide (AEA) that lacks the hydroxyethyl moiety. It was hydrolyzed by FAAH more effectively than AEA but exhibited significantly weaker binding to the human CB1 receptor with a Ki of 9.6 μM . Arachidonoyl amide exhibited similar binding and translocation into cells via the AEA transporter compared to AEA. Arachidonoyl amide inhibited [3H]-AEA uptake into human astrocytoma cells with an IC50 of 9 μM .

Product information

CAS Number: 85146-53-8

Molecular Weight: 303.48

Formula: C20H33NO

Chemical Name: (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenamide



InChi: InChI=1S/C20H33NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H2,21,22)/b7-6-,10-9-,13-12-,16-15-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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