Ro 20-1724


Catalog No. Size PriceQuantity
M23068-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Ro 20-1724 is a cell-permeable, cAMP-specific phosphodiesterase type IV (PDE4) inhibitor (IC50 = 2 µM)., It weakly inhibits PDE3 with a Ki value greater than 25 µM.1 Ro 20-1724 inhibits the release of cytokines and other inflammatory signals as well as prevents the development of reactive oxygen species. It is often used to study cAMP-related functions in vascular cells.

Product information

CAS Number: 29925-17-5

Molecular Weight: 278.35

Formula: C15H22N2O3

Chemical Name: (4S)-4-[(3-butoxy-4-methoxyphenyl)methyl]imidazolidin-2-one

Smiles: COC1C=CC(C[C@H]2CNC(=O)N2)=CC=1OCCCC

InChiKey: PDMUULPVBYQBBK-LBPRGKRZSA-N

InChi: InChI=1S/C15H22N2O3/c1-3-4-7-20-14-9-11(5-6-13(14)19-2)8-12-10-16-15(18)17-12/h5-6,9,12H,3-4,7-8,10H2,1-2H3,(H2,16,17,18)/t12-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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