Cytochrome P450 CYP1B1 (190-198) [Homo sapiens]


Catalog No. Size PriceQuantity
M23391-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

H2N-FLDPRPLTV-OH Cytochrome P450 CYP1B1 is a dioxin-inducible form of the cytochrome P450 family of xenobiotic metabolizing enzymes1. HLA-A2 restricted, CYP1B1 190–198 (CYP190) peptide specific T cell responses are induced in HLA-A2Kb transgenic mice by immunization with ZYC300, a PLG microparticle formulation that contains a plasmid DNA encoding the tumor associated antigen CYP1B12, 3. Each successive co-application of EPT contributes to an escalating T cell response that can be observed 2 weeks after the last immunization, and that even a single EPT when given with the usually ineffective 30 µg dose of ZYC300 was able to induce a detectable CD8+ CYP190 specific T cell response4.

Product information

Molecular Weight: 1057.24

Formula: C50H80N12O13

Chemical Name: 3-[2-(2-amino-3-phenylpropanamido)-4-methylpentanamido]-4-(2-{[5-carbamimidamido-1-(2-{[1-({1-[(1-carboxy-2-methylpropyl)carbamoyl]-2-hydroxypropyl}carbamoyl)-3-methylbutyl]carbamoyl}pyrrolidin-1-yl)-1-oxopentan-2-yl]carbamoyl}pyrrolidin-1-yl)-4-oxobutanoic acid

Smiles: CC(O)C(NC(=O)C(CC(C)C)NC(=O)C1CCCN1C(=O)C(CCCNC(N)=N)NC(=O)C1CCCN1C(=O)C(CC(O)=O)NC(=O)C(CC(C)C)NC(=O)C(N)CC1C=CC=CC=1)C(=O)NC(C(C)C)C(O)=O

InChiKey: AFURROFZOZKVAF-UHFFFAOYSA-N

InChi: InChI=1S/C50H80N12O13/c1-26(2)22-33(56-41(66)31(51)24-30-14-9-8-10-15-30)42(67)58-35(25-38(64)65)48(73)62-21-13-17-36(62)44(69)55-32(16-11-19-54-50(52)53)47(72)61-20-12-18-37(61)45(70)57-34(23-27(3)4)43(68)60-40(29(7)63)46(71)59-39(28(5)6)49(74)75/h8-10,14-15,26-29,31-37,39-40,63H,11-13,16-25,51H2,1-7H3,(H,55,69)(H,56,66)(H,57,70)(H,58,67)(H,59,71)(H,60,68)(H,64,65)(H,74,75)(H4,52,53,54)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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