Angiotensin 1/2 (1-8) amide


Catalog No. Size PriceQuantity
M23399-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

The physiologically active peptide angiotensin-2 (angiotensin 1- 8) is yielded from angiotensin-1, a substrate of ACE (angiotensin converting enzyme), by removing a dipeptide. Angiotensin 1/2 (1-8) amide (H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-amide) is a peptide analogue to angiotensin II that is used as a vasopressor agent in the treatment of certain types of shock and circulatory collapse. It is a potent vasoconstrictor and is used as a cardiac stimulant.

Product information

CAS Number: 96593-18-9

Molecular Weight: 1045.19

Formula: C50H72N14O11

Chemical Name: (3S)-3-amino-3-{[(1S)-4-carbamimidamido-1-{[(1S)-1-{[(1S)-1-{[(1S,2S)-1-{[(2S)-1-[(2S)-2-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]carbamoyl}-2-methylbutyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}-2-methylpropyl]carbamoyl}butyl]carbamoyl}propanoic acid

Smiles: CC(C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC(O)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O

InChiKey: VTVVSXYHDIVLKI-JZXHSEFVSA-N

InChi: InChI=1S/C50H72N14O11/c1-5-28(4)41(48(74)61-37(23-31-25-55-26-57-31)49(75)64-20-10-14-38(64)46(72)59-35(42(52)68)21-29-11-7-6-8-12-29)63-45(71)36(22-30-15-17-32(65)18-16-30)60-47(73)40(27(2)3)62-44(70)34(13-9-19-56-50(53)54)58-43(69)33(51)24-39(66)67/h6-8,11-12,15-18,25-28,33-38,40-41,65H,5,9-10,13-14,19-24,51H2,1-4H3,(H2,52,68)(H,55,57)(H,58,69)(H,59,72)(H,60,73)(H,61,74)(H,62,70)(H,63,71)(H,66,67)(H4,53,54,56)/t28-,33-,34-,35-,36-,37-,38-,40-,41-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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