hemagglutinin (332-340) [Influenza A virus]


Catalog No. Size PriceQuantity
M23429-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Influenza hemagglutinin (HA) is a type of hemagglutinin found on the surface of the influenza viruses. It is an antigenic glycoprotein. It is responsible for binding the virus to the cell that is being infected. HA proteins bind to cells with sialic acid on the membranes, such as cells in the upper respiratory tract or erythrocytes. HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of host endosomal membrane with the viral membrane. Since hemagglutinin is the major surface protein of the influenza A virus and is essential to the entry process, it is the primary target of neutralizing antibodies.

Product information

Molecular Weight: 970.12

Formula: C42H75N13O13

Chemical Name: 2-{2-[(1-{2-[2-(2-{2-[2-(2-amino-3-hydroxybutanamido)acetamido]-4-methylpentanamido}-5-carbamimidamidopentanamido)-3-carbamoylpropanamido]-3-methylpentanoyl}pyrrolidin-2-yl)formamido]-3-hydroxypropanamido}-3-methylpentanoic acid

Smiles: CC(C)CC(NC(=O)CNC(=O)C(N)C(C)O)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(N)=O)C(=O)NC(C(C)CC)C(=O)N1CCCC1C(=O)NC(CO)C(=O)NC(C(C)CC)C(O)=O

InChiKey: MJWIWVDWJZGQJA-UHFFFAOYSA-N

InChi: InChI=1S/C42H75N13O13/c1-8-21(5)32(40(66)55-15-11-13-28(55)38(64)52-27(19-56)37(63)54-33(41(67)68)22(6)9-2)53-36(62)26(17-29(43)58)51-34(60)24(12-10-14-47-42(45)46)50-35(61)25(16-20(3)4)49-30(59)18-48-39(65)31(44)23(7)57/h20-28,31-33,56-57H,8-19,44H2,1-7H3,(H2,43,58)(H,48,65)(H,49,59)(H,50,61)(H,51,60)(H,52,64)(H,53,62)(H,54,63)(H,67,68)(H4,45,46,47)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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