Description
Influenza hemagglutinin (HA) is a type of hemagglutinin found on the surface of the influenza viruses. It is an antigenic glycoprotein. It is responsible for binding the virus to the cell that is being infected. HA proteins bind to cells with sialic acid on the membranes, such as cells in the upper respiratory tract or erythrocytes. HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of host endosomal membrane with the viral membrane. Since hemagglutinin is the major surface protein of the influenza A virus and is essential to the entry process, it is the primary target of neutralizing antibodies.
Product information
Molecular Weight: 970.12
Formula: C42H75N13O13
Chemical Name: 2-{2-[(1-{2-[2-(2-{2-[2-(2-amino-3-hydroxybutanamido)acetamido]-4-methylpentanamido}-5-carbamimidamidopentanamido)-3-carbamoylpropanamido]-3-methylpentanoyl}pyrrolidin-2-yl)formamido]-3-hydroxypropanamido}-3-methylpentanoic acid
Smiles: CC(C)CC(NC(=O)CNC(=O)C(N)C(C)O)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(N)=O)C(=O)NC(C(C)CC)C(=O)N1CCCC1C(=O)NC(CO)C(=O)NC(C(C)CC)C(O)=O
InChiKey: MJWIWVDWJZGQJA-UHFFFAOYSA-N
InChi: InChI=1S/C42H75N13O13/c1-8-21(5)32(40(66)55-15-11-13-28(55)38(64)52-27(19-56)37(63)54-33(41(67)68)22(6)9-2)53-36(62)26(17-29(43)58)51-34(60)24(12-10-14-47-42(45)46)50-35(61)25(16-20(3)4)49-30(59)18-48-39(65)31(44)23(7)57/h20-28,31-33,56-57H,8-19,44H2,1-7H3,(H2,43,58)(H,48,65)(H,49,59)(H,50,61)(H,51,60)(H,52,64)(H,53,62)(H,54,63)(H,67,68)(H4,45,46,47)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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