prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens]

Catalog No. Size PriceQuantity
M23451-C Contact for quotation $100Unavailable


prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens], (C26H41N9O9), a peptide with the sequence H2N-Ala-Thr-Gly-Gly-Tyr-Arg-OH, MW= 623.66. Prostate apoptosis response-4 (Par-4), is a human gene coding for a tumor-suppressor protein that induces apoptosis in cancer cells, but not in normal cells.The tumor suppressor PAR-4 represses and activates transcription. The protein encoded by this gene is a PAR-4-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of PAR-4. This protein is specifically upregulated during apoptosis of prostate cells1.The active domain of the Par-4 protein has been found to confer cancer resistance in transgenic mice without compromising normal viability or aging, and may have therapeutic significance2.

Product information

Molecular Weight: 623.66

Formula: C26H41N9O9

Chemical Name: 2-[2-(2-{2-[2-(2-aminopropanamido)-3-hydroxybutanamido]acetamido}acetamido)-3-(4-hydroxyphenyl)propanamido]-5-carbamimidamidopentanoic acid

Smiles: CC(O)C(NC(=O)C(C)N)C(=O)NCC(=O)NCC(=O)NC(CC1C=CC(O)=CC=1)C(=O)NC(CCCNC(N)=N)C(O)=O


InChi: InChI=1S/C26H41N9O9/c1-13(27)22(40)35-21(14(2)36)24(42)32-11-19(38)31-12-20(39)33-18(10-15-5-7-16(37)8-6-15)23(41)34-17(25(43)44)4-3-9-30-26(28)29/h5-8,13-14,17-18,21,36-37H,3-4,9-12,27H2,1-2H3,(H,31,38)(H,32,42)(H,33,39)(H,34,41)(H,35,40)(H,43,44)(H4,28,29,30)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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