ASP6432


Catalog No. Size PriceQuantity
M23481-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

ASP6432 is a potent and selective type 1 lysophosphatidic acid receptor (LPA1) antagonist with IC50s of 11 nM and 30 nM for human LPA1 and rat LPA1, respectively.

Product information

CAS Number: 1282549-08-9

Molecular Weight: 598.78

Formula: C26H31KN4O6S2

Chemical Name: potassium (2-{[1-(3,5-dimethoxy-4-methylphenyl)-N-(3-phenylpropyl)formamido]methyl}-1,3-thiazole-4-carbonyl)(ethylsulfamoyl)azanide

Smiles: [K+].CC1C(=CC(=CC=1OC)C(=O)N(CC1=NC(=CS1)C(=O)[N-]S(=O)(=O)NCC)CCCC1C=CC=CC=1)OC

InChiKey: WKYBXXHNGOTYDD-UHFFFAOYSA-M

InChi: InChI=1S/C26H32N4O6S2.K/c1-5-27-38(33,34)29-25(31)21-17-37-24(28-21)16-30(13-9-12-19-10-7-6-8-11-19)26(32)20-14-22(35-3)18(2)23(15-20)36-4;/h6-8,10-11,14-15,17,27H,5,9,12-13,16H2,1-4H3,(H,29,31);/q;+1/p-1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 250 mg/mL (417.52 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

ASP6432 inhibits the LPA-induced proliferation of human prostate stromal cells.

Products are for research use only. Not for human use.

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