Iodoacetamide-PEG3-azide


Catalog No. Size PriceQuantity
M23527-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Iodoacetamide-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1594986-04-5

Molecular Weight: 386.19

Formula: C10H19IN4O4

Chemical Name: N-(2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethyl)-2-iodoacetamide

Smiles: [N-]=[N+]=NCCOCCOCCOCCNC(=O)CI

InChiKey: MVKSZBZLUGCWFA-UHFFFAOYSA-N

InChi: InChI=1S/C10H19IN4O4/c11-9-10(16)13-1-3-17-5-7-19-8-6-18-4-2-14-15-12/h1-9H2,(H,13,16)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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