Fmoc-amino-PEG3-CH2COOH


Catalog No. Size PriceQuantity
M23562-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Fmoc-amino-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 139338-72-0

Molecular Weight: 429.46

Formula: C23H27NO7

Chemical Name: 2-(2-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethoxy]ethoxy}ethoxy)acetic acid

Smiles: OC(=O)COCCOCCOCCNC(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21

InChiKey: XNOJSAOJCBOZTA-UHFFFAOYSA-N

InChi: InChI=1S/C23H27NO7/c25-22(26)16-30-14-13-29-12-11-28-10-9-24-23(27)31-15-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-8,21H,9-16H2,(H,24,27)(H,25,26)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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