Catalog No. Size PriceQuantity
M23577-C Contact sales@xcessbio.com for quotation $100Unavailable


G150 is a potent and highly selective human cyclic GMP-AMP synthase (h-cGAS) inhibitor for repression of dsDNA-triggered interferon expression, with an IC50 of 10.2 nM.

Product information

CAS Number: 2369751-30-2

Molecular Weight: 391.25

Formula: C18H16Cl2N4O2

Chemical Name: 1-[9-(6-aminopyridin-3-yl)-6,7-dichloro-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-2-yl]-2-hydroxyethan-1-one

Smiles: NC1=CC=C(C=N1)C1C=C(Cl)C(Cl)=C2NC3CCN(CC=3C=12)C(=O)CO


InChi: InChI=1S/C18H16Cl2N4O2/c19-12-5-10(9-1-2-14(21)22-6-9)16-11-7-24(15(26)8-25)4-3-13(11)23-18(16)17(12)20/h1-2,5-6,23,25H,3-4,7-8H2,(H2,21,22)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 125 mg/mL (319.49 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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