Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane


Catalog No. Size PriceQuantity
M23646-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1421933-29-0

Molecular Weight: 778.93

Formula: C36H66N4O14

Chemical Name: tert-butyl 3-[2-(1-azido-3,6,9,12-tetraoxapentadecan-15-amido)-3-[3-(tert-butoxy)-3-oxopropoxy]-2-{[3-(tert-butoxy)-3-oxopropoxy]methyl}propoxy]propanoate

Smiles: CC(C)(C)OC(=O)CCOCC(COCCC(=O)OC(C)(C)C)(COCCC(=O)OC(C)(C)C)NC(=O)CCOCCOCCOCCOCCN=[N+]=[N-]

InChiKey: WXDPDERWOTZNLB-UHFFFAOYSA-N

InChi: InChI=1S/C36H66N4O14/c1-33(2,3)52-30(42)11-16-49-26-36(27-50-17-12-31(43)53-34(4,5)6,28-51-18-13-32(44)54-35(7,8)9)39-29(41)10-15-45-20-22-47-24-25-48-23-21-46-19-14-38-40-37/h10-28H2,1-9H3,(H,39,41)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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