PEG2-bis(phosphonic acid diethyl ester)


Catalog No. Size PriceQuantity
M23711-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

PEG2-bis(phosphonic acid diethyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 500347-73-9

Molecular Weight: 378.29

Formula: C12H28O9P2

Chemical Name: {[(2-{2-[(diethoxyphosphoryl)oxy]ethoxy}ethoxy)(ethoxy)phosphoryl]oxy}ethane

Smiles: CCOP(=O)(OCC)OCCOCCOP(=O)(OCC)OCC

InChiKey: CJAGHBDQWWLWAX-UHFFFAOYSA-N

InChi: InChI=1S/C12H28O9P2/c1-5-16-22(13,17-6-2)20-11-9-15-10-12-21-23(14,18-7-3)19-8-4/h5-12H2,1-4H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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