Description
Erythrosine B is an artificial dye widely used in the food and textile industries. Erythrosine B is also a novel photosensitizer which has been used to develop animal models.
Product information
CAS Number: 16423-68-0
Molecular Weight: 879.86
Formula: C20H6I4Na2O5
Chemical Name: disodium 2',4',5',7'-tetraiodo-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-3',6'-bis(olate)
Smiles: [Na+].[Na+].[O-]C1=C(I)C2OC3=C(C=C(I)C([O-])=C3I)C3(OC(=O)C4=CC=CC=C34)C=2C=C1I
InChiKey: RAGZEDHHTPQLAI-UHFFFAOYSA-L
InChi: InChI=1S/C20H8I4O5.2Na/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20;;/h1-6,25-26H;;/q;2*+1/p-2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 33.33 mg/mL (37.88 mM; Need ultrasonic). H2O : 33.33 mg/mL (37.88 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Only the two highest concentrations of Erythrosine B tested (50.0 and 70.0 μg/mL) are significantly different (p<0.05) from the vehicle control group when the Tail Moment and Tail Intensity, which represent the extent of DNA damage, are analyzed. Results show increased micronuclei (MNi) frequencies at six of the seven Erythrosine B concentrations (0.2 to 70.0 μg/mL) when compare to vehicle control group.
Products are for research use only. Not for human use.
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