Description
PNU112455A hydrochloride is an ATP-competitive CDK2 and CDK5 inhibitor. PNU112455A hydrochloride binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.
Product information
CAS Number: 21886-12-4
Molecular Weight: 301.75
Formula: C10H12ClN5O2S
Chemical Name: 4-[(6-aminopyrimidin-4-yl)amino]benzene-1-sulfonamide hydrochloride
Smiles: Cl.NC1=CC(NC2=CC=C(C=C2)S(N)(=O)=O)=NC=N1
InChiKey: XBXQRCJKDCEQBS-UHFFFAOYSA-N
InChi: InChI=1S/C10H11N5O2S.ClH/c11-9-5-10(14-6-13-9)15-7-1-3-8(4-2-7)18(12,16)17;/h1-6H,(H2,12,16,17)(H3,11,13,14,15);1H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 125 mg/mL (414.25 mM; Need ultrasonic). H2O : 20 mg/mL (66.28 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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