Catalog No. Size PriceQuantity
M24001-C Contact sales@xcessbio.com for quotation $100Unavailable


EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET).

Product information

CAS Number: 50402-56-7

Molecular Weight: 266.32

Formula: C12H14N2O3S

Chemical Name: 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid

Smiles: NCCNC1=CC=CC2C1=CC=CC=2S(O)(=O)=O


InChi: InChI=1S/C12H14N2O3S/c13-7-8-14-11-5-1-4-10-9(11)3-2-6-12(10)18(15,16)17/h1-6,14H,7-8,13H2,(H,15,16,17)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 13.89 mg/mL (52.16 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

The peptide sequence of EDANS is derived from a natural processing site for HIV-1 PR. Incubation of recombinant HIV-1 PR with the fluorogenic substrate resulted in specific cleavage at the Tyr-Pro bond and a time-dependent increase in fluorescence intensity that was linearly related to the extent of substrate hydrolysis.

Products are for research use only. Not for human use.

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